Creating a new method to quickly test protein variations for useful applications
Official title: Development of a high throughput platform for screening directed evolution libraries
Funded at University of California Santa Cruz · NIH-10755739 · Data updated 2026-11-12
This study is working on a faster way to create and test different versions of proteins, which could help scientists find new treatments and products that might benefit patients like you in the future.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Santa Cruz NIH-funded |
| Lab location | 1 site (Santa Cruz, United States) |
| Project start | January 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $135,382 |
| NIH project number | 5R21GM148870-02 |
| Project ID | NIH-10755739 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that could be treated by novel proteins or therapies developed through this technology.
✕Less likely to help
Patients with conditions unrelated to protein therapies or those not requiring biochemical interventions may not receive any benefit from this research.
What this research studies
This research focuses on improving the process of directed evolution, which allows scientists to create and test many variations of proteins to find those with desirable traits for industrial and therapeutic uses. By developing a high throughput platform, the researchers aim to streamline the screening process of these protein variants, making it faster and more efficient. This involves using advanced analytical techniques to evaluate the biochemical properties of thousands of protein mutants, ultimately leading to the discovery of new biomolecules that can be used in various applications. Patients may benefit indirectly from this research as it could lead to the development of new therapies or industrial products derived from these proteins.
Why it matters
Potential benefit: If successful, this research could lead to the rapid development of new proteins that can be used in medical treatments or industrial processes.
How similar studies have gone: Other research has shown success in using directed evolution techniques, indicating that this approach has the potential for significant advancements.
Where this research is happening
-
University of California Santa Cruz
Santa Cruz, United States Active
Researchers
- Principal investigator: Sanchez, Laura Margaret — University of California Santa Cruz
- Study coordinator: Sanchez, Laura Margaret
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.