Creating a new method to produce therapeutic exosomes for drug delivery
A Scalable Continuous Production Platform for Large-Scale Manufacturing of Therapeutic Exosomes
['FUNDING_R21'] · UNIVERSITY OF NOTRE DAME · NIH-10739425
This study is working on a new way to make tiny delivery vehicles called exosomes that can help carry medicine directly to the right cells in your body, making treatments more effective and reliable for patients.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF NOTRE DAME (nih funded) |
| Locations | 1 site (NOTRE DAME, UNITED STATES) |
| Trial ID | NIH-10739425 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new platform for the large-scale production of therapeutic exosomes, which are tiny vesicles that can deliver drugs to specific cells in the body. The approach involves using a three-dimensional scaffold to enhance exosome production, a special material to improve drug loading efficiency, and a filtration system to isolate the exosomes with high purity and yield. By addressing current limitations in exosome production, this project aims to create a reliable method for producing these promising drug delivery vehicles for clinical use.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who require advanced drug delivery methods for their treatments, particularly those with conditions that could benefit from targeted therapies.
Not a fit: Patients who do not require drug delivery systems or those with conditions that are not addressed by exosome-based therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted drug delivery systems, improving treatment outcomes for patients.
How similar studies have performed: Other research has shown promise in using exosomes for drug delivery, but this specific approach to scalable production is relatively novel.
Where this research is happening
NOTRE DAME, UNITED STATES
- UNIVERSITY OF NOTRE DAME — NOTRE DAME, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, YICHUN — UNIVERSITY OF NOTRE DAME
- Study coordinator: WANG, YICHUN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.