Creating a new material to improve oxygen delivery in medical treatments
Engineering a novel biomaterial for oxygen transport applications
This study is working on a new type of material that can help carry oxygen in the body, which could be used as a safer alternative to red blood cells for people who need blood transfusions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project ID | NIH-10757888 on NIH RePORTER |
What this research studies
This research focuses on developing a novel biomaterial designed to enhance oxygen transport in medical applications, particularly as a substitute for red blood cells in transfusions. The approach involves engineering hemoglobin-based oxygen carriers that aim to minimize adverse effects such as vasoconstriction and oxidative damage, which are common with existing products. By optimizing the size and composition of these carriers, the research seeks to improve their safety and efficacy for patients requiring blood transfusions. The methodology includes advanced polymerization techniques and thorough testing to evaluate the performance of these new materials in biological systems.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who require blood transfusions, particularly those with conditions that necessitate red blood cell replacement.
Not a fit: Patients who do not require blood transfusions or have conditions unrelated to oxygen transport may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective blood substitutes that improve patient outcomes during transfusions.
How similar studies have performed: Previous research has shown promise in developing hemoglobin-based oxygen carriers, but this specific approach aims to address significant limitations observed in earlier products.
Where this research is happening
Columbus, UNITED STATES
- Ohio State University — Columbus, United States (Active)
Researchers
- Principal investigator: Palmer, Andre Francis — Ohio State University
- Study coordinator: Palmer, Andre Francis
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.