Creating a new injectable antibiotic for serious drug-resistant infections

Development of a Novel Injectable Antibiotic to Treat Serious Multidrug-resistant Gram-positive Infections

['FUNDING_SBIR_1'] · AIMMAX THERAPEUTICS, INC. · NIH-10837145

This study is testing a new antibiotic called AMX-2005 to see if it can help treat serious infections caused by tough bacteria like MRSA and VRE, giving hope to patients who need better options when current treatments don’t work.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorAIMMAX THERAPEUTICS, INC. (nih funded)
Locations1 site (DURHAM, UNITED STATES)
Trial IDNIH-10837145 on ClinicalTrials.gov

What this research studies

This research focuses on developing a novel antibiotic, AMX-2005, aimed at treating serious infections caused by multidrug-resistant gram-positive bacteria, such as MRSA and VRE. The approach involves testing the antibiotic's effectiveness in laboratory settings and in animal models to ensure it can effectively kill these resistant bacteria. By targeting pathogens that have become resistant to existing treatments, this research aims to provide new therapeutic options for patients suffering from severe infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients suffering from infections caused by multidrug-resistant gram-positive bacteria.

Not a fit: Patients with infections caused by bacteria that are not gram-positive or those who do not have antibiotic-resistant infections may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a new treatment option for patients with serious infections caused by antibiotic-resistant bacteria.

How similar studies have performed: Previous research has shown success in developing new antibiotics targeting resistant bacteria, indicating a promising avenue for this novel approach.

Where this research is happening

DURHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.