Creating a new imaging tool to study metabolism in tissues and how they respond to treatment
Development of CapCell Scope for Metabolic Imaging of Tissue Heterogeneity and Therapy Response
This study is testing a new imaging tool called CapCell that helps doctors see how cancer treatments affect the metabolism of tissues without needing any invasive procedures, making it easier to understand how well the treatments are working.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11141209 on NIH RePORTER |
What this research studies
This research focuses on developing a novel imaging platform called CapCell that allows for non-invasive observation of metabolic changes in tissues. By utilizing advanced optical imaging techniques, the study aims to quantify how cellular metabolism shifts in response to different therapies, particularly in cancer treatment. The approach seeks to improve access to metabolic imaging by enabling studies to be conducted in various settings, from laboratories to clinical environments, without the need for specialized facilities. This could enhance our understanding of how tissues respond to treatments over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients undergoing treatment for cancer or other metabolic conditions who may benefit from improved imaging techniques.
Not a fit: Patients with stable conditions that do not involve metabolic changes or those not undergoing treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatment monitoring for patients with metabolic disorders or cancer.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for metabolic studies, indicating that this approach could yield significant insights.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Ramanujam, Nirmala — Duke University
- Study coordinator: Ramanujam, Nirmala
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.