Creating a new imaging tool for a specific receptor linked to multiple sclerosis and bladder cancer
Development of PET radiotracer for imaging sphingosine-1-phosphate receptor 2 (S1PR2)
This study is testing a new imaging tool that helps doctors see how a specific receptor in the body works, which could improve the way we understand and treat conditions like multiple sclerosis and bladder cancer, ultimately helping patients keep better track of their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10914200 on NIH RePORTER |
What this research studies
This research focuses on developing a small molecule PET radiotracer that can be used for in vivo imaging of the Sphingosine-1-phosphate receptor 2 (S1PR2). By targeting this receptor, the research aims to enhance our understanding of its role in diseases such as multiple sclerosis and bladder cancer. The approach involves using advanced imaging techniques to visualize the receptor's activity in the body, which could lead to better diagnosis and treatment strategies. Patients may benefit from improved monitoring of their conditions through this innovative imaging method.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with multiple sclerosis or bladder cancer who are seeking advanced imaging options.
Not a fit: Patients with conditions unrelated to S1PR2 or those who do not have access to the imaging technology may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new way to visualize and understand the progression of multiple sclerosis and bladder cancer, leading to more effective treatments.
How similar studies have performed: Other research has shown promise in using PET imaging for similar receptors, indicating a potential for success in this novel approach.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Tu, Zhude — Washington University
- Study coordinator: Tu, Zhude
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.