Creating a new imaging platform to study cell structures in detail
Official title: Development of a Versatile Multiplexing Nanoscopy Platform for Cell Biology
Funded at Yale University · NIH-10934358 · Data updated 2026-11-12
This study is working on a new way to take super-detailed pictures of tiny parts inside our cells, which can help us see how diseases like cancer and Alzheimer's affect them, making it easier for scientists to understand these conditions better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 25, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $572,800 |
| NIH project number | 5R01GM151829-02 |
| Project ID | NIH-10934358 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Alzheimer's disease or other neurological disorders, as well as cancer patients.
✕Less likely to help
Patients with conditions unrelated to cellular function or those not requiring advanced imaging techniques may not benefit from this research.
What this research studies
This research focuses on developing an advanced imaging technique called super-resolution microscopy to visualize cellular structures with high precision. By improving the ability to observe how organelles change in diseases like cancer and Alzheimer's, the project aims to create a versatile platform that can analyze multiple cellular components simultaneously. The approach involves designing new probes and automated systems to enhance imaging speed, resolution, and cost-effectiveness, ultimately allowing for a more comprehensive understanding of cellular functions and disease mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and diagnosing diseases at the cellular level, potentially improving treatment strategies for conditions like Alzheimer's and cancer.
How similar studies have gone: Previous research has shown promise in using super-resolution microscopy techniques, indicating that this approach could lead to significant advancements in cellular imaging.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Bewersdorf, Joerg — Yale University
- Study coordinator: Bewersdorf, Joerg
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.