Creating a new heart support system for babies and young children

Development of the Inspired Therapeutics NeoMate Mechanical Circulatory Support System for Neonates and Infants

NIH-funded research Inspired Therapeutics, LLC · NIH-10709884

This study is working on a small heart support device called NeoMate that helps newborns and infants with heart failure, giving them a better chance to stay healthy while they wait for a heart transplant.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionInspired Therapeutics, LLC NIH-funded
Lab location1 site (Charlottesville, UNITED STATES)
Project IDNIH-10709884 on NIH RePORTER

What this research studies

This research focuses on developing the NeoMate Mechanical Circulatory Support System, specifically designed for neonates and infants suffering from heart failure. The project aims to create a compact device that can assist the heart for up to 30 days, using advanced technology to ensure safety and effectiveness. The NeoMate system includes a miniature pump and a smart controller that monitors the device's performance. By improving mechanical support options for very young patients, this research seeks to enhance their chances of survival while waiting for a heart transplant.

Who could benefit from this research

Good fit: Ideal candidates for this research are neonates and infants under 10 kg who are experiencing heart failure and may require mechanical circulatory support.

Not a fit: Patients who are older than 21 years or those who do not have heart failure will not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve survival rates for infants and neonates with heart failure by providing a reliable temporary heart support solution.

How similar studies have performed: Previous research has shown promise in developing mechanical circulatory support devices for pediatric patients, but this specific approach with the NeoMate system is innovative and aims to fill a critical gap in treatment options.

Where this research is happening

Charlottesville, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.