Creating a new heart pump system for patients with heart failure

Development of a Universal Bi-ventricular Replacement System for the Failing Heart

NIH-funded research Pennsylvania State Univ Hershey Med Ctr · NIH-10896124

This study is testing a new type of implantable blood pump that can help people with severe heart failure by taking over the job of the heart, making it easier for smaller patients to live better and longer with fewer complications.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionPennsylvania State Univ Hershey Med Ctr NIH-funded
Lab location1 site (Hershey, United States)
Project IDNIH-10896124 on NIH RePORTER

What this research studies

This research focuses on developing an innovative implantable blood pump system designed to replace the heart in patients with severe heart failure. The system consists of separate pumps for the left and right sides of the heart, which work together to meet the body's changing needs. By utilizing advanced technology, the pumps aim to provide reliable operation for at least a decade while minimizing complications such as blood clots and bleeding. This approach is particularly beneficial for smaller patients and aims to improve overall heart function and patient quality of life.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals suffering from severe heart failure who are not suitable for traditional heart transplant options.

Not a fit: Patients with mild heart failure or those who are not candidates for heart replacement therapies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly enhance the treatment options for patients with end-stage heart failure, potentially improving their survival and quality of life.

How similar studies have performed: Previous research on left ventricular assist devices has shown promise, indicating that innovative pump systems can improve outcomes for heart failure patients.

Where this research is happening

Hershey, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.