NIH-funded research NIH-funded research

Creating a new formulation to improve flu vaccines

Official title: DEVELOPMENT OF VESIVAX CO-ADJUVANT FORMULATION OF 2E151 for flu vaccines

Funded at Molecular Express, INC. · NIH-10933265 · Data updated 2026-11-12

This study is testing a new type of flu vaccine that uses special ingredients to boost your immune response, aiming to provide better protection against the flu, especially during flu season.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMolecular Express, INC.
NIH-funded
Lab location1 site (Rancho Dominguez, United States)
Project startSeptember 30, 2023
Project endSeptember 29, 2025
Funding year2023
Award (this year)$599,925
NIH project number75N93023C00033-0-9999-1
Project IDNIH-10933265 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who are at higher risk for influenza, such as the elderly, young children, or those with compromised immune systems.

Less likely to help

Patients who are not at risk for influenza or those who have already received a flu vaccine may not benefit from this research.

What this research studies

This research focuses on developing a new formulation for flu vaccines that combines signal modifiers with a specific lipid to enhance the immune response. Using a proprietary liposomal system called VesiVax, the researchers aim to create a more effective vaccine that can better protect against the influenza virus. Patients may benefit from improved vaccine efficacy, leading to better protection during flu seasons. The research involves laboratory work primarily with animal models to test the new vaccine formulation.

Why it matters

Potential benefit: If successful, this research could lead to more effective flu vaccines that provide better protection against influenza.

How similar studies have gone: Other research has shown promise in enhancing vaccine efficacy through similar approaches, indicating potential for success in this area.

Where this research is happening

  • Molecular Express, INC.
    Rancho Dominguez, United States
    Active

Researchers

  • Principal investigator: Onho, Sam — Molecular Express, INC.
  • Study coordinator: Onho, Sam

Related research

Other NIH-funded projects on the same topics.

  • Developing a new vaccine adjuvant to enhance immune response against gonorrhea and aspergillosis

    This study is working on a new helper ingredient for vaccines called ME-M-006, which aims to make vaccines more effective against infections like gonorrhea and a type of fungus, so that people can have better protection when they get vaccinated.

    NIH research Molecular Express, INC. · Rancho Dominguez, United States · NIH-11203954

  • Creating new HIV vaccines using advanced delivery systems

    This study is working on new HIV vaccines that use tiny particles to help your immune system recognize and fight the virus better, so you could get a stronger and more effective vaccine in the future.

    NIH research Molecular Express, INC. · Rancho Dominguez, United States · NIH-11172342

  • Developing a synthetic lung surfactant for preterm infants

    This study is testing a new treatment called ME-1001, a synthetic lung surfactant, to help preterm babies with respiratory distress syndrome breathe better and stay healthier.

    NIH research Molecular Express, INC. · Rancho Dominguez, United States · NIH-11086104

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.