Creating a new digital tool to measure ion channels in cells
A Digital and Open-Source Amplifier for Oocyte Ion Channel Measurements
['FUNDING_R15'] · UNIVERSITY OF ST. THOMAS · NIH-10114033
This study is working on a new digital tool to help scientists better measure ion channels, which are important for understanding brain diseases, making it easier for labs to do their experiments and get accurate results.
Quick facts
| Phase | ['FUNDING_R15'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ST. THOMAS (nih funded) |
| Locations | 1 site (ST. PAUL, UNITED STATES) |
| Trial ID | NIH-10114033 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a digital amplifier designed to enhance the measurement of ion channels, which are vital for understanding neurological diseases. By utilizing a specific technique called Cut-Open Vaseline Gap (COVG), the project aims to automate and simplify the experimental setup, making it more accessible for various laboratories. The new amplifier will allow for real-time adjustments during experiments, improving the efficiency and accuracy of data collection related to ion channel behavior. This innovative approach could significantly advance the field of electrophysiology.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with neurological conditions that involve ion channel dysfunction.
Not a fit: Patients with conditions unrelated to ion channel activity may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for neurological diseases by providing better tools for studying ion channels.
How similar studies have performed: Other research has successfully utilized digital tools for electrophysiological measurements, indicating a promising direction for this innovative approach.
Where this research is happening
ST. PAUL, UNITED STATES
- UNIVERSITY OF ST. THOMAS — ST. PAUL, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: KOERNER, LUCAS J — UNIVERSITY OF ST. THOMAS
- Study coordinator: KOERNER, LUCAS J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.