Creating a new diagnostic tool for quick and accurate biomarker detection.
Development of a Novel Split Enzyme Diagnostic Platform for Use at the Point of Care
['FUNDING_OTHER'] · CLEMSON UNIVERSITY · NIH-11182852
This study is working on a new, easy-to-use test that can quickly and affordably detect important health markers right where you receive care, helping doctors make better decisions without needing costly lab tests.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CLEMSON UNIVERSITY (nih funded) |
| Locations | 1 site (CLEMSON, UNITED STATES) |
| Trial ID | NIH-11182852 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a novel diagnostic platform that allows for rapid and cost-effective detection of biomarkers directly at the point of care. By utilizing innovative protein-based signaling networks, the project aims to enhance the sensitivity of detecting low concentrations of proteins and small molecules, which are crucial for accurate clinical decision-making. The approach involves combining split enzyme reconstitution, autocatalytic feedback loops, and small molecule biosensors to create a system that can amplify signals for better detection. This could potentially reduce reliance on expensive lab tests and improve the accuracy of diagnoses.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals requiring rapid diagnostic testing for various medical conditions that involve biomarker detection.
Not a fit: Patients with conditions that do not involve detectable biomarkers or those who are not in need of point-of-care testing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and timely diagnoses for patients, improving treatment outcomes.
How similar studies have performed: Previous research has shown promise in using protein-based signaling for diagnostics, indicating that this approach could be a significant advancement in the field.
Where this research is happening
CLEMSON, UNITED STATES
- CLEMSON UNIVERSITY — CLEMSON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MAJORS, CATHERINE E. — CLEMSON UNIVERSITY
- Study coordinator: MAJORS, CATHERINE E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.