Creating a new device to support heart function in patients with severe heart failure.
Development of a Minimally Invasive Single Cannulation, Compact Single Port Pulsatile Ventricular Assist Device (sppVAD) for Total LV Support
This study is testing a new, easy-to-use device that helps people with cardiogenic shock by supporting their heart while letting them move around, making it easier for them to recover and feel better.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | W-Z Biotech, LLC NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project ID | NIH-10922122 on NIH RePORTER |
What this research studies
This research focuses on developing a minimally invasive device designed to support patients experiencing cardiogenic shock, a life-threatening condition characterized by low heart output. The new device aims to provide total left ventricle support while allowing patients to move around freely, which is crucial for their recovery. By bridging patients to recovery or further treatment options, this device could significantly improve their quality of life. The approach involves engineering a compact, single-port device that can be inserted with minimal surgical intervention.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients suffering from severe cardiogenic shock who require temporary mechanical circulatory support.
Not a fit: Patients with stable heart function or those not experiencing cardiogenic shock may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a revolutionary device that improves survival rates and quality of life for patients with severe heart failure.
How similar studies have performed: While there have been advancements in mechanical circulatory support devices, this specific approach is novel and aims to address significant gaps in current treatment options.
Where this research is happening
Lexington, United States
- W-Z Biotech, LLC — Lexington, United States (Active)
Researchers
- Principal investigator: Topaz, Stephen R — W-Z Biotech, LLC
- Study coordinator: Topaz, Stephen R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.