Creating a new device to sample and analyze gut bacteria and their effects on health

Development and clinical evaluation of the CapScan gastrointestinal sampling device for metabolomics monitoring

NIH-funded research Envivo Bio INC · NIH-10910862

This study is testing a new capsule that you can swallow to help doctors learn more about the tiny germs in your gut and how they affect your digestion, with hopes of making it a regular tool for understanding gut issues like SIBO.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEnvivo Bio INC NIH-funded
Lab location1 site (San Carlos, United States)
Project IDNIH-10910862 on NIH RePORTER

What this research studies

This research focuses on developing the CapScan gastrointestinal sampling capsule, an innovative ingestible device designed to collect and analyze the microbiota within the gastrointestinal (GI) tract. By monitoring how gut microbes transform food products, the study aims to enhance our understanding of various gastrointestinal disorders. The device will undergo rigorous testing for safety and effectiveness in healthy volunteers before being used in studies involving patients with conditions like small intestinal bacterial overgrowth (SIBO). Ultimately, the goal is to make this technology as commonplace in medical practice as blood tests.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals experiencing gastrointestinal disorders, particularly those with small intestinal bacterial overgrowth (SIBO).

Not a fit: Patients without gastrointestinal issues or those not undergoing antibiotic treatment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved monitoring and treatment of gastrointestinal disorders through better understanding of gut microbiota.

How similar studies have performed: Similar research has shown promise in utilizing microbiota analysis for understanding gut health, suggesting that this approach could be effective.

Where this research is happening

San Carlos, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.