Creating a new device to sample and analyze gut bacteria and their effects on health
Official title: Development and clinical evaluation of the CapScan gastrointestinal sampling device for metabolomics monitoring
Funded at Envivo Bio INC · NIH-10910862 · Data updated 2026-11-12
This study is testing a new capsule that you can swallow to help doctors learn more about the tiny germs in your gut and how they affect your digestion, with hopes of making it a regular tool for understanding gut issues like SIBO.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Envivo Bio INC NIH-funded |
| Lab location | 1 site (San Carlos, United States) |
| Project start | April 1, 2022 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $569,684 |
| NIH project number | 5R33CA260665-03 |
| Project ID | NIH-10910862 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals experiencing gastrointestinal disorders, particularly those with small intestinal bacterial overgrowth (SIBO).
✕Less likely to help
Patients without gastrointestinal issues or those not undergoing antibiotic treatment may not benefit from this research.
What this research studies
This research focuses on developing the CapScan gastrointestinal sampling capsule, an innovative ingestible device designed to collect and analyze the microbiota within the gastrointestinal (GI) tract. By monitoring how gut microbes transform food products, the study aims to enhance our understanding of various gastrointestinal disorders. The device will undergo rigorous testing for safety and effectiveness in healthy volunteers before being used in studies involving patients with conditions like small intestinal bacterial overgrowth (SIBO). Ultimately, the goal is to make this technology as commonplace in medical practice as blood tests.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and treatment of gastrointestinal disorders through better understanding of gut microbiota.
How similar studies have gone: Similar research has shown promise in utilizing microbiota analysis for understanding gut health, suggesting that this approach could be effective.
Where this research is happening
-
Envivo Bio INC
San Carlos, United States Active
Researchers
- Principal investigator: Shalon, Tidhar Dari — Envivo Bio INC
- Study coordinator: Shalon, Tidhar Dari
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.