Creating a new device to help babies with heart defects breathe better
DEVELOPMENT OF A PULMONARY FLOW RESTRICTOR FOR HYPOPLASTIC LEFT HEART SYNDROME
['FUNDING_SBIR_2'] · STARLIGHT CARDIOVASCULAR, INC. · NIH-11059188
This study is testing a new, less invasive device to help babies with Hypoplastic Left Heart Syndrome by controlling blood flow to their lungs, which could help them grow stronger before needing more surgeries.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STARLIGHT CARDIOVASCULAR, INC. (nih funded) |
| Locations | 1 site (San Diego, UNITED STATES) |
| Trial ID | NIH-11059188 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a percutaneous flow restrictor designed to replace the traditional surgical banding method for infants with congenital heart defects, specifically Hypoplastic Left Heart Syndrome. The device aims to reduce excessive blood flow to the lungs, allowing for a more balanced circulation between the lungs and the rest of the body. By using a less invasive approach, the goal is to improve the survival rates of newborns and minimize damage to their pulmonary arteries, ultimately enabling them to grow stronger before undergoing further surgeries. The research involves testing the device's effectiveness and safety in clinical settings.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns diagnosed with congenital heart defects, particularly those with Hypoplastic Left Heart Syndrome.
Not a fit: Patients who are older than infancy or those without congenital heart defects may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer, less invasive treatment option for infants with congenital heart defects, improving their chances of survival and overall health.
How similar studies have performed: Previous attempts to create percutaneous solutions for similar conditions have shown promising results, indicating potential for success with this approach.
Where this research is happening
San Diego, UNITED STATES
- STARLIGHT CARDIOVASCULAR, INC. — San Diego, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: TANG, BEVERLY — STARLIGHT CARDIOVASCULAR, INC.
- Study coordinator: TANG, BEVERLY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.