Creating a new device to assist patients with heart circulation issues.
Official title: Development of a Percutaneous Double Lumen Cannula-Based Cavopulmonary Assist System Toward Clinical Application
Funded at University of Kentucky · NIH-11019787 · Data updated 2026-11-12
This study is working on a new device to help people with cavopulmonary failure after heart surgery, making it easier for them to get around without needing more major surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Kentucky NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project start | February 1, 2024 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $596,904 |
| NIH project number | 5R01HL168085-02 |
| Project ID | NIH-11019787 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have undergone a total cavopulmonary connection and are experiencing cavopulmonary failure.
✕Less likely to help
Patients who do not have a history of single ventricle defects or those who are not experiencing cavopulmonary failure may not benefit from this research.
What this research studies
This research focuses on developing a new percutaneous double lumen cannula system designed to assist patients with cavopulmonary failure, a condition that can arise after certain heart surgeries. The device aims to provide total ambulatory support by connecting to the existing heart structure without the need for major surgery. The research involves designing and optimizing the cannula to minimize complications and ensure effective performance. By using advanced modeling techniques, the team will tailor the device to fit individual patient anatomies.
Why it matters
Potential benefit: If successful, this research could significantly improve the quality of life and survival rates for patients suffering from cavopulmonary failure.
How similar studies have gone: While the approach of developing a percutaneous assist device is innovative, similar technologies have shown promise in other cardiac applications, indicating potential for success.
Where this research is happening
-
University of Kentucky
Lexington, United States Active
Researchers
- Principal investigator: Wang, Dongfang — University of Kentucky
- Study coordinator: Wang, Dongfang
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.