Creating a network to improve emergency care clinical trials
Official title: Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN)
Funded at Johns Hopkins University · NIH-11059050 · Data updated 2026-11-12
This study is setting up a new network of hospitals to improve emergency care for patients with serious health issues, like heart and brain problems, by making it easier to include a wide range of people in clinical trials.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $361,149 |
| NIH project number | 5U24NS129499-03 |
| Project ID | NIH-11059050 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include individuals experiencing neurologic, cardiac, respiratory, hematologic, or traumatic conditions, particularly from minority and socioeconomically disadvantaged backgrounds.
✕Less likely to help
Patients with non-emergency conditions or those not presenting to the emergency department may not benefit from this research.
What this research studies
This research aims to establish a new Clinical Center organized by Johns Hopkins Medicine to enhance emergency care clinical trials through a Hub-and-Spoke network. The network will consist of nine partner institutions and over 25 clinical sites across five states and Washington, DC, allowing for the recruitment of a diverse patient population. With an annual emergency department census exceeding 1.6 million visits, the project focuses on improving outcomes for patients with various critical conditions, including cardiac and neurologic issues. The research will leverage extensive clinical experience and a robust institutional environment to contribute to national emergency care initiatives.
Why it matters
Potential benefit: If successful, this research could lead to improved emergency care protocols and better outcomes for patients experiencing critical health conditions.
How similar studies have gone: Previous research has shown success in improving emergency care through similar collaborative networks, indicating a promising approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Kelen, Gabor D — Johns Hopkins University
- Study coordinator: Kelen, Gabor D
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.