Creating a network to improve emergency care clinical trials

Network for Emergency Care Clinical Trials: Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN)

['FUNDING_OTHER'] · JOHNS HOPKINS UNIVERSITY · NIH-11059050

This study is setting up a new network of hospitals to improve emergency care for patients with serious health issues, like heart and brain problems, by making it easier to include a wide range of people in clinical trials.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorJOHNS HOPKINS UNIVERSITY (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11059050 on ClinicalTrials.gov

What this research studies

This research aims to establish a new Clinical Center organized by Johns Hopkins Medicine to enhance emergency care clinical trials through a Hub-and-Spoke network. The network will consist of nine partner institutions and over 25 clinical sites across five states and Washington, DC, allowing for the recruitment of a diverse patient population. With an annual emergency department census exceeding 1.6 million visits, the project focuses on improving outcomes for patients with various critical conditions, including cardiac and neurologic issues. The research will leverage extensive clinical experience and a robust institutional environment to contribute to national emergency care initiatives.

Who could benefit from this research

Good fit: Ideal candidates for participation include individuals experiencing neurologic, cardiac, respiratory, hematologic, or traumatic conditions, particularly from minority and socioeconomically disadvantaged backgrounds.

Not a fit: Patients with non-emergency conditions or those not presenting to the emergency department may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved emergency care protocols and better outcomes for patients experiencing critical health conditions.

How similar studies have performed: Previous research has shown success in improving emergency care through similar collaborative networks, indicating a promising approach.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.