NIH-funded research NIH-funded research

Creating a nasal vaccine to prevent gonorrhea

Official title: DEVELOPMENT OF AN INTRANASAL VACCINE AGAINST GONORRHEA

Funded at Intravacc B.v. · NIH-10919579 · Data updated 2026-11-12

This study is working on a new nose spray vaccine to help prevent gonorrhea, a common sexually transmitted infection, and if it works well in tests, it could offer a simple way to protect people from getting this infection.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIntravacc B.v.
NIH-funded
Lab location1 site (Bilthoven, Netherlands)
Project startSeptember 21, 2022
Project endJanuary 14, 2026
Funding year2023
Award (this year)$756,750
NIH project number75N93022C00058-P00002-9999-1
Project IDNIH-10919579 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals at risk of gonorrhea infection, including sexually active adults and adolescents.

Less likely to help

Patients who are not sexually active or those who have already been vaccinated against gonorrhea may not benefit from this research.

What this research studies

This research focuses on developing an intranasal vaccine aimed at preventing gonorrhea, a common sexually transmitted infection. The approach involves formulating and manufacturing vaccine components, followed by rigorous testing for safety and effectiveness in animal models. If successful, this vaccine could provide a non-invasive method for immunization against gonorrhea, potentially reducing the incidence of this infection in the population.

Why it matters

Potential benefit: If successful, this research could lead to a new, effective vaccine that helps prevent gonorrhea infections.

How similar studies have gone: While there have been successful vaccine developments for other infectious diseases, this specific approach for gonorrhea is relatively novel and untested.

Where this research is happening

  • Intravacc B.v.
    Bilthoven, Netherlands
    Active

Researchers

  • Principal investigator: Oosterhoff, Dinja — Intravacc B.v.
  • Study coordinator: Oosterhoff, Dinja

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.