Creating a model to study neonatal cardiac arrest and resuscitation effects
Developing and characterizing a translational neonatal rat cardiac arrest and cardiopulmonary resuscitation model
This study is looking at how cardiac arrest and CPR can affect the brains of newborns, using baby rats to find better ways to help improve their recovery and long-term health after such events.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10591062 on NIH RePORTER |
What this research studies
This research focuses on developing a neonatal rat model to better understand the effects of cardiac arrest and cardiopulmonary resuscitation (CPR) on brain injury in newborns. By simulating conditions similar to those seen in clinical settings, the researchers aim to investigate how global ischemia affects brain regions and overall neurological outcomes. The study will explore potential therapies to improve long-term outcomes for neonates who experience cardiac arrest, addressing a significant gap in current treatment options.
Who could benefit from this research
Good fit: Ideal candidates for this research are neonates who have experienced cardiac arrest or are at high risk for such events.
Not a fit: Patients who are older than neonates or those without a history of cardiac arrest may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies that enhance neurological recovery in newborns who suffer from cardiac arrest.
How similar studies have performed: While there have been advancements in neonatal care, this specific model for studying cardiac arrest in neonates is novel and has not been extensively tested in previous research.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Quillinan, Nidia — University of Colorado Denver
- Study coordinator: Quillinan, Nidia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.