Creating a model to improve treatment for severe bleeding after trauma

Development of a multi-scale closed loop model for hemorrhagic shock: a platform to assess REBOA performance

NIH-funded research Texas Engineering Experiment Station · NIH-11177979

This study is working on a new computer model to help doctors better manage severe bleeding after injuries, which could lead to better treatments for patients in emergencies.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTexas Engineering Experiment Station NIH-funded
Lab location1 site (College Station, United States)
Project IDNIH-11177979 on NIH RePORTER

What this research studies

This research focuses on developing a new computational model to better understand and manage hemorrhagic shock, a critical condition that can lead to death after traumatic injuries. By simulating the body's response to severe bleeding, the researchers aim to optimize the use of a technique called Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA), which helps control blood loss. The model will allow for testing different scenarios without the need for extensive animal studies, potentially speeding up the development of effective treatments. Patients may benefit from improved strategies for managing severe bleeding during emergencies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have suffered traumatic injuries leading to severe hemorrhagic shock.

Not a fit: Patients with non-traumatic causes of bleeding or those who are not experiencing hemorrhagic shock may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for patients experiencing severe bleeding, potentially saving lives.

How similar studies have performed: Previous research has shown promise in using computational models for similar medical challenges, indicating potential for success in this novel approach.

Where this research is happening

College Station, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.