NIH-funded research R01 grant

Creating a model to improve treatment for severe bleeding after trauma

Official title: Development of a multi-scale closed loop model for hemorrhagic shock: a platform to assess REBOA performance

Funded at Texas Engineering Experiment Station · NIH-11055517 · Data updated 2026-11-12

This study is working on a new computer model to help doctors better manage severe bleeding after injuries, using a technique called REBOA to control the bleeding and improve patient care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionTexas Engineering Experiment Station
NIH-funded
Lab location1 site (College Station, United States)
Project startJune 10, 2024
Project endJuly 31, 2027
Funding year2024
Award (this year)$596,743
NIH project number7R01HL162633-03
Project IDNIH-11055517 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who have suffered traumatic injuries leading to hemorrhagic shock, particularly in military or emergency settings.

Less likely to help

Patients with non-traumatic causes of bleeding or those who are not experiencing hemorrhagic shock may not benefit from this research.

What this research studies

This research focuses on developing a new computational model to better understand and manage hemorrhagic shock, a critical condition that can occur after traumatic injuries. By simulating the body's physiological responses to severe bleeding, the study aims to optimize the use of a technique called Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA), which helps control bleeding in emergency situations. The model will help identify the best practices for using REBOA, including the size and timing of balloon inflation, to minimize complications and improve patient outcomes. This innovative approach seeks to accelerate advancements in treatment without relying solely on costly animal studies.

Why it matters

Potential benefit: If successful, this research could lead to improved survival rates and better recovery outcomes for patients experiencing severe traumatic bleeding.

How similar studies have gone: While the use of computational models in medical research is gaining traction, this specific approach to optimizing REBOA is relatively novel and has not been extensively tested in prior studies.

Where this research is happening

  • Texas Engineering Experiment Station
    College Station, United States
    Active

Researchers

  • Principal investigator: Rahbar, Elaheh — Texas Engineering Experiment Station
  • Study coordinator: Rahbar, Elaheh

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.