Creating a model to improve treatment for severe bleeding after trauma
Development of a multi-scale closed loop model for hemorrhagic shock: a platform to assess REBOA performance
This study is working on a new computer model to help doctors better manage severe bleeding after injuries, using a technique called REBOA to control the bleeding and improve patient care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Engineering Experiment Station NIH-funded |
| Lab location | 1 site (College Station, United States) |
| Project ID | NIH-11055517 on NIH RePORTER |
What this research studies
This research focuses on developing a new computational model to better understand and manage hemorrhagic shock, a critical condition that can occur after traumatic injuries. By simulating the body's physiological responses to severe bleeding, the study aims to optimize the use of a technique called Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA), which helps control bleeding in emergency situations. The model will help identify the best practices for using REBOA, including the size and timing of balloon inflation, to minimize complications and improve patient outcomes. This innovative approach seeks to accelerate advancements in treatment without relying solely on costly animal studies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have suffered traumatic injuries leading to hemorrhagic shock, particularly in military or emergency settings.
Not a fit: Patients with non-traumatic causes of bleeding or those who are not experiencing hemorrhagic shock may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and better recovery outcomes for patients experiencing severe traumatic bleeding.
How similar studies have performed: While the use of computational models in medical research is gaining traction, this specific approach to optimizing REBOA is relatively novel and has not been extensively tested in prior studies.
Where this research is happening
College Station, United States
- Texas Engineering Experiment Station — College Station, United States (Active)
Researchers
- Principal investigator: Rahbar, Elaheh — Texas Engineering Experiment Station
- Study coordinator: Rahbar, Elaheh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.