Creating a miniaturized model of a human joint to study arthritis
Official title: Microphysiological joint-on-chip platform for the study of arthritic diseases
Funded at University of Colorado · NIH-10976945 · Data updated 2026-11-12
This study is creating a tiny model of a human joint to help researchers understand arthritis better and find new treatments faster, so people with joint pain can get relief sooner.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado NIH-funded |
| Lab location | 1 site (Boulder, UNITED STATES) |
| Project start | August 15, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $618,629 |
| NIH project number | 1R01AR083379-01A1 |
| Project ID | NIH-10976945 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from arthritis or related joint diseases who are seeking new treatment options.
✕Less likely to help
Patients with joint conditions unrelated to arthritis may not benefit from this research.
What this research studies
This research aims to develop a microphysiological 'joint-on-chip' system that mimics the structure and function of a human joint. By using advanced technologies, the project will create a realistic model that can replicate the mechanical and biological responses of joint tissues. This model will allow researchers to study the mechanisms of arthritic diseases and quickly test new treatment options, potentially speeding up the process of bringing effective therapies to patients.
Why it matters
Potential benefit: If successful, this research could lead to faster and more effective treatments for arthritis, improving the quality of life for millions of patients.
How similar studies have gone: Other research has shown promise in using similar on-chip technologies for studying various diseases, indicating a potential for success in this novel approach.
Where this research is happening
-
University of Colorado
Boulder, United States Active
Researchers
- Principal investigator: Neu, Corey P — University of Colorado
- Study coordinator: Neu, Corey P
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.