Creating a method for cloning marmosets to aid biomedical research
Establishment of Somatic Cell Nuclear Transfer as a Universal Platform for Cloning Marmosets
This study is working on a new way to create cloned marmosets, which are small monkeys that can help us learn more about brain diseases like Alzheimer's, so we can better understand and treat these conditions in people.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-10682479 on NIH RePORTER |
What this research studies
This research focuses on developing a universal platform for cloning common marmosets, a type of non-human primate that shares many physiological and genetic similarities with humans. By utilizing somatic cell nuclear transfer, the researchers aim to create genetically engineered marmosets that can help bridge the gap between mouse models and human studies in neuroscience. The project will explore the genetic causes of neurological disorders using these cloned marmosets, which are known for their complex brain functions and social behaviors. This approach could enhance our understanding of conditions like Alzheimer's disease and other chronic neurological disorders.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with neurological and neuropsychiatric disorders, as well as those interested in advancements in genetic research.
Not a fit: Patients with conditions unrelated to neurological disorders may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in understanding and treating neurological disorders in humans.
How similar studies have performed: Previous research has shown success in using genetically engineered marmosets for studying neurological disorders, indicating a promising approach.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Park, Jung Eun — University of Pittsburgh at Pittsburgh
- Study coordinator: Park, Jung Eun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.