Creating a mathematical model to understand obesity-related diabetes and wound healing
Mathematical Models for Obesity-Induced Type 2 Diabetes Mellitus and Chronic Wound Healing
['FUNDING_OTHER'] · ROCHESTER INSTITUTE OF TECHNOLOGY · NIH-10937272
This study is looking at how being overweight affects healing for people with type 2 diabetes, and it aims to create a helpful tool to better understand and improve care for those dealing with diabetes and slow-healing wounds.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ROCHESTER INSTITUTE OF TECHNOLOGY (nih funded) |
| Locations | 1 site (ROCHESTER, UNITED STATES) |
| Trial ID | NIH-10937272 on ClinicalTrials.gov |
What this research studies
This research aims to develop a predictive mathematical model that explores the relationship between obesity, type 2 diabetes, and chronic wound healing. By incorporating key physiological factors and a detailed analysis of glucose and glycogen exchange in the liver, the project seeks to better understand how obesity contributes to these conditions. The model will focus on dynamic variables rather than constant parameters, allowing for a more accurate representation of the factors that impair healing in diabetes patients. This innovative approach could lead to improved strategies for managing diabetes and related complications.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 65 and older who are experiencing obesity and related complications such as type 2 diabetes and chronic wounds.
Not a fit: Patients who are not affected by obesity or do not have diabetes or chronic wounds may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management and treatment options for patients suffering from obesity-related diabetes and chronic wounds.
How similar studies have performed: While the approach of using mathematical modeling in this context is innovative, similar studies have shown promise in understanding complex interactions in diabetes management.
Where this research is happening
ROCHESTER, UNITED STATES
- ROCHESTER INSTITUTE OF TECHNOLOGY — ROCHESTER, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SIEWE, NOURRIDINE — ROCHESTER INSTITUTE OF TECHNOLOGY
- Study coordinator: SIEWE, NOURRIDINE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Adult-Onset Diabetes Mellitus