NIH-funded research R01 grant

Creating a fully automated system for managing blood sugar in Type 1 diabetes

Official title: Advanced Artificial Pancreas Systems to Enable Fully Automated Glycemic Control in Type 1 Diabetes Mellitus

Funded at University of Virginia · NIH-10909039 · Data updated 2026-11-12

This study is working on a smart device that helps people with Type 1 diabetes manage their blood sugar automatically, so they won’t have to worry about counting carbs or announcing meals, making life a little easier for them.

More Diabetes research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Virginia
NIH-funded
Lab location1 site (Charlottesville, United States)
Project startSeptember 12, 2021
Project endJuly 31, 2026
Funding year2024
Award (this year)$617,546
NIH project number5R01DK129553-04
Project IDNIH-10909039 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with Type 1 diabetes who require insulin therapy.

Less likely to help

Patients with Type 2 diabetes or those who do not require insulin therapy may not benefit from this research.

What this research studies

This research aims to develop an advanced artificial pancreas system that automates blood sugar control for individuals with Type 1 diabetes. By utilizing pattern recognition technology, the system anticipates meals and adjusts insulin delivery proactively, rather than reactively. This approach seeks to eliminate the need for patients to manually announce meals or count carbohydrates, thereby simplifying diabetes management. The project includes pilot studies and a larger main study to evaluate the effectiveness of faster-acting insulin analogs in this automated system.

Why it matters

Potential benefit: If successful, this research could significantly improve glycemic control and reduce the burden of diabetes management for patients.

How similar studies have gone: Previous research has shown promise in automated insulin delivery systems, making this approach a continuation of successful advancements in diabetes management.

Where this research is happening

  • University of Virginia
    Charlottesville, United States
    Active

Researchers

  • Principal investigator: Breton, Marc D — University of Virginia
  • Study coordinator: Breton, Marc D

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.