Creating a diverse panel of rat models for studying diseases
Hybrid Rat Diversity Program
This study is working to improve how scientists use rats in research by creating a diverse group of rat strains and collecting important genetic information, which will help them better understand and find treatments for different diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project ID | NIH-11015009 on NIH RePORTER |
What this research studies
This research aims to enhance the use of rat models in clinical settings by establishing a diverse panel of rat strains and a comprehensive genomic dataset. The project involves creating a Hybrid Rat Diversity Panel (HRDP) that includes various inbred strains, which will be characterized and maintained for research purposes. Researchers will have access to biobanked tissues and genomic data to study complex disease traits, enabling better understanding and potential treatments for various conditions. The data will be made available through the Rat Genome Database, facilitating further research and analysis.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with conditions that are studied using animal models, such as addiction, anxiety, and various chronic diseases.
Not a fit: Patients with conditions that do not have a relevant animal model or are not studied in this research may not receive any benefit.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for complex diseases affecting humans.
How similar studies have performed: Other research has successfully utilized diverse animal models to advance understanding of complex diseases, indicating that this approach has potential for significant impact.
Where this research is happening
Milwaukee, United States
- Medical College of Wisconsin — Milwaukee, United States (Active)
Researchers
- Principal investigator: Dwinell, Melinda R — Medical College of Wisconsin
- Study coordinator: Dwinell, Melinda R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.