Creating a digital model to track and predict pediatric neuroblastoma tumors

A digital twin to track and predict the evolution of pediatric neuroblastoma tumors

NIH-funded research Dana-Farber Cancer Inst · NIH-11059442

This study is creating a digital model of neuroblastoma tumors in kids to better understand how they grow and respond to treatment, helping doctors personalize cancer therapies using targeted radiation.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionDana-Farber Cancer Inst NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11059442 on NIH RePORTER

What this research studies

This research focuses on developing a digital twin of neuroblastoma tumors in children, which will help in tracking tumor evolution and predicting responses to treatment. By using advanced computational models, the project aims to enhance the effectiveness of radiopharmaceutical therapy, a targeted cancer treatment that uses radioactive substances. The digital twin will simulate how tumors behave and respond to radiation, providing valuable insights for personalized treatment plans. This innovative approach seeks to fill existing gaps in the application of digital models in pediatric oncology.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years diagnosed with neuroblastoma.

Not a fit: Patients with neuroblastoma who are older than 11 years or those with other types of cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for children with neuroblastoma.

How similar studies have performed: Other research has shown promise in using digital twins for cancer treatment, indicating that this approach could be a significant advancement in pediatric oncology.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
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Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.