Creating a digital model to track and predict pediatric neuroblastoma tumors
Official title: A digital twin to track and predict the evolution of pediatric neuroblastoma tumors
Funded at Dana-Farber Cancer Inst · NIH-11059442 · Data updated 2026-11-12
This study is creating a digital model of neuroblastoma tumors in kids to better understand how they grow and respond to treatment, helping doctors personalize cancer therapies using targeted radiation.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dana-Farber Cancer Inst NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 19, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $249,999 |
| NIH project number | 3U54CA274516-02S1 |
| Project ID | NIH-11059442 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children aged 0-11 years diagnosed with neuroblastoma.
✕Less likely to help
Patients with neuroblastoma who are older than 11 years or those with other types of cancer may not benefit from this research.
What this research studies
This research focuses on developing a digital twin of neuroblastoma tumors in children, which will help in tracking tumor evolution and predicting responses to treatment. By using advanced computational models, the project aims to enhance the effectiveness of radiopharmaceutical therapy, a targeted cancer treatment that uses radioactive substances. The digital twin will simulate how tumors behave and respond to radiation, providing valuable insights for personalized treatment plans. This innovative approach seeks to fill existing gaps in the application of digital models in pediatric oncology.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment strategies for children with neuroblastoma.
How similar studies have gone: Other research has shown promise in using digital twins for cancer treatment, indicating that this approach could be a significant advancement in pediatric oncology.
Where this research is happening
-
Dana-Farber Cancer Inst
Boston, United States Active
Researchers
- Principal investigator: Michor, Franziska — Dana-Farber Cancer Inst
- Study coordinator: Michor, Franziska
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.