Creating a digital model to improve treatment for right ventricular dysfunction
Official title: A Digital Hemodynamic Twin for Right Ventricular Dysfunction
Funded at Massachusetts General Hospital · NIH-11070361 · Data updated 2026-11-12
This study is creating a digital tool that acts like a twin of your heart's right ventricle to help doctors better understand and treat heart problems, using real-time data from patients to improve care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 8, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $490,001 |
| NIH project number | 5R01HL173129-02 |
| Project ID | NIH-11070361 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with right ventricular dysfunction or related cardiovascular conditions.
✕Less likely to help
Patients with stable cardiovascular health or those without any signs of right ventricular dysfunction may not benefit from this research.
What this research studies
This research aims to develop a digital 'hemodynamic twin' that simulates the cardiovascular system, specifically focusing on the right ventricle. By using detailed hemodynamic data, the project seeks to create a computational model that can help physicians make better clinical decisions regarding the management of right ventricular dysfunction. The model will be continuously updated with new patient data, allowing for real-time insights into the patient's cardiovascular health. This innovative approach could enhance the understanding of complex interactions within the cardiovascular system and improve treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and personalized treatment strategies for patients with right ventricular dysfunction.
How similar studies have gone: Other research has shown promise in using computational models for cardiovascular health, indicating that this approach could be a significant advancement in the field.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Houstis, Nicholas E. — Massachusetts General Hospital
- Study coordinator: Houstis, Nicholas E.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.