Creating a digital model for rectal cancer to improve radiotherapy
A Digital Twin for rectal cancer to guide adaptive radiotherapy
['FUNDING_OTHER'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11059810
This study is looking for patients with rectal cancer to help create a digital model that can personalize and improve radiotherapy treatments by examining how their immune system responds to radiation therapy.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11059810 on ClinicalTrials.gov |
What this research studies
This research aims to develop a digital twin model for rectal cancer that can help personalize and enhance radiotherapy treatments. By collecting and analyzing tumor biopsies, blood samples, and other biological data from patients undergoing preoperative short course radiotherapy, the study will explore how the immune system interacts with radiation therapy. Patients will participate in a clinical trial where their samples will be used to understand the effects of radiation on cancer and surrounding tissues, potentially leading to more effective treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with rectal cancer who are scheduled to undergo preoperative short course radiotherapy.
Not a fit: Patients with rectal cancer who are not eligible for preoperative short course radiotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more tailored and effective radiotherapy treatments for rectal cancer patients.
How similar studies have performed: Previous research has shown promise in using digital models and biological data to enhance cancer treatment, indicating that this approach could be effective.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FORMENTI, SILVIA C. — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: FORMENTI, SILVIA C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.