Creating a diary tool to track symptoms of diarrhea in irritable bowel syndrome.
Official title: Preparation and Submission Support of a Full Qualification Package (FQP) for the Diary for Irritable Bowel Syndrome Symptoms—Diarrhea (DIBSS-D) (DDT #000148)
Funded at Critical Path Institute · NIH-10833930 · Data updated 2026-11-12
This study is creating a helpful diary tool for people with diarrhea-predominant irritable bowel syndrome (IBS-D) to track their symptoms and experiences, so that we can better understand their needs and improve treatment options.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Critical Path Institute NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $249,979 |
| NIH project number | 1U01FD008074-01 |
| Project ID | NIH-10833930 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with irritable bowel syndrome, particularly those experiencing predominant diarrhea.
✕Less likely to help
Patients with irritable bowel syndrome who do not experience diarrhea or those with other gastrointestinal disorders may not benefit from this research.
What this research studies
This research focuses on developing a comprehensive diary tool specifically designed to track symptoms of diarrhea in patients with irritable bowel syndrome (IBS-D). The project involves gathering insights from patients to identify the most relevant symptoms and experiences associated with IBS-D. By conducting interviews and reviewing existing literature, the research aims to create a standardized measure that can help in assessing the severity of symptoms and improve treatment options for patients. Ultimately, this tool will support regulatory approval processes for new therapies targeting IBS-D.
Why it matters
Potential benefit: If successful, this research could lead to better symptom management and treatment options for patients suffering from IBS-D.
How similar studies have gone: Previous research has successfully developed similar patient-reported outcome measures for other conditions, indicating a promising approach for this project.
Where this research is happening
-
Critical Path Institute
Tucson, United States Active
Researchers
- Principal investigator: Eremenco, Sonya — Critical Path Institute
- Study coordinator: Eremenco, Sonya
Related research
Other NIH-funded projects on the same topics.
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Identifying biomarkers for diarrhea-predominant irritable bowel syndrome using stool samples
This study is looking to make it easier to diagnose diarrhea-predominant irritable bowel syndrome (IBS-D) by checking stool samples for certain markers, so if you have IBS-D, researchers want to find a simple and non-invasive way to help identify your condition better.
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Investigating how certain dietary sugars affect diarrhea in IBS patients
This study is looking at how certain carbohydrates called FODMAPs affect people with diarrhea-predominant Irritable Bowel Syndrome (IBS-D) and aims to find out how a low FODMAP diet can help ease their symptoms, so patients may be asked to try different diets and share their experiences.
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PediCODE: A Biorepository and Consortium for CoDE - Congenital Diarrhea and Enteropathy
A nationwide effort to collect clinical data and patient-derived samples to uncover the genetic causes of congenital diarrhea and enteropathy and to build a resource that helps researchers study these diseases.
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PediCODE Consortium and Biobank for Congenital Diarrhea and Enteropathy
Creating a multi-center team and biobank to find genetic causes of congenital diarrhea and enteropathy in children and collect samples that can help future research.
-
Mobile health tool to guide dehydration care for acute diarrhea across all ages
A mobile app uses AI to help people of all ages determine dehydration risk during acute diarrhea and guide rehydration decisions.
-
Understanding how certain gut bacteria cause diarrhea in children and how it works in the gut lining
This project looks at how infections from ETEC and EPEC bacteria cause diarrhea, especially in children, and uses a mouse model and human-derived gut cell systems to uncover the underlying mechanisms.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.