NIH-funded research Sbir 2 grant

Creating a device to monitor and identify cells in lab cultures

Official title: Development of an impedance-based cell assurance monitor to aid in identifying and characterizing cells in tissue culture

Funded at Applied Biophysics, INC. · NIH-10917933 · Data updated 2026-11-12

This study is testing a new device called the Cell Assurance Monitor (CAM) that helps scientists make sure the animal cells they use in research are healthy and not contaminated, so they can get better and more reliable results in their experiments.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionApplied Biophysics, INC.
NIH-funded
Lab location1 site (Troy, United States)
Project startJuly 1, 2024
Project endJune 30, 2026
Funding year2024
Award (this year)$947,705
NIH project number1R44GM154507-01
Project IDNIH-10917933 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are researchers and laboratories that work with animal cell cultures and require high-quality cell identification and monitoring.

Less likely to help

Patients who are not involved in laboratory research or do not work with cell cultures may not benefit from this research.

What this research studies

This research focuses on improving the quality of animal cells used in scientific studies by developing a device called the Cell Assurance Monitor (CAM). The CAM uses electrical impedance measurements to detect issues such as misidentified cells and contamination by microorganisms. By analyzing the impedance data at various frequencies, the device can provide insights into cell morphology and behavior, helping researchers identify potential problems before they affect experimental outcomes. This innovative approach aims to enhance the reliability of cell culture techniques in biomedical research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate and reliable results in scientific studies involving cell cultures.

How similar studies have gone: Previous studies have shown success in using impedance measurements for cell identification and contamination detection, indicating a promising approach.

Where this research is happening

  • Applied Biophysics, INC.
    Troy, United States
    Active

Researchers

  • Principal investigator: Keese, Charles R — Applied Biophysics, INC.
  • Study coordinator: Keese, Charles R

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.