Creating a device to mimic natural hormone cycles in cell cultures
Official title: Autonomous Platform for Pulsatile Soluble Stimulation
Funded at University of California-Irvine · NIH-11056882 · Data updated 2026-11-12
This study is creating a special device that mimics the natural hormone changes in our bodies to help scientists better understand how cells behave and how diseases develop, which could lead to better treatments for patients like you.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project start | March 15, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $211,950 |
| NIH project number | 5R21TR005032-02 |
| Project ID | NIH-11056882 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that are influenced by hormonal cycles, such as diabetes or reproductive disorders.
✕Less likely to help
Patients who do not have conditions related to hormonal regulation or who are not involved in research studies may not benefit from this research.
What this research studies
This research focuses on developing an innovative cell culture device that replicates the natural hormonal cycles found in the human body. By mimicking these cycles, the device aims to provide a more accurate environment for studying cell behavior and disease processes. The system will automatically cycle culture media and monitor cellular responses to hormonal pulses, allowing researchers to capture rapid changes in cell behavior. This approach could significantly enhance our understanding of various diseases and improve therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments by providing a better understanding of diseases through improved cell culture methods.
How similar studies have gone: While the approach of mimicking hormonal cycles in cell cultures is innovative, similar methodologies have shown promise in enhancing biological research, indicating potential for success.
Where this research is happening
-
University of California-Irvine
Irvine, United States Active
Researchers
- Principal investigator: Hui, Elliot E — University of California-Irvine
- Study coordinator: Hui, Elliot E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.