Creating a detailed map of lung diseases to improve understanding and treatment.
BioRepository for INvestigation of Diseases of the Lung (BRINDL) - Phase III
This study is creating a detailed map of the human lung to help scientists learn more about how healthy lungs work and what goes wrong in lung diseases, so they can better understand and treat conditions that affect both kids and adults.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10975581 on NIH RePORTER |
What this research studies
This research aims to build a comprehensive molecular and cellular atlas of the human lung, which will help researchers understand both normal lung biology and the pathobiology of various lung diseases. By collecting and analyzing human lung tissues, the project seeks to identify critical cellular components and molecular pathways involved in lung diseases, including those affecting children and adults. The research will utilize advanced techniques for preserving and studying these tissues, facilitating collaborations to enhance the understanding of lung conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with lung diseases such as asthma, bronchopulmonary dysplasia, and COVID-19 related pneumonia, as well as healthy individuals for comparison.
Not a fit: Patients with non-respiratory conditions or those who do not have access to the research facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the discovery of new treatments and therapies for various lung diseases, improving patient outcomes.
How similar studies have performed: Other research initiatives have successfully utilized similar approaches to create biological atlases, indicating potential for success in this novel project.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Pryhuber, Gloria S — University of Rochester
- Study coordinator: Pryhuber, Gloria S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.