Creating a detailed 3D map of the human lung
Synthesis of the Multi-Modality High Resolution 3-D Atlas of Human Lung
This study is creating a detailed 3D map of the human lung to help us understand how healthy lungs work compared to diseased ones, which could lead to better treatments for lung conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10917164 on NIH RePORTER |
What this research studies
This research aims to develop a comprehensive, high-resolution 3D atlas of the human lung, which will enhance our understanding of lung biology at the cellular and molecular levels. By utilizing advanced techniques like single-cell sequencing and multi-modal imaging, the project will generate detailed maps that illustrate the various cell types and their functions within the lung. This atlas will serve as a reference point for comparing healthy lung tissue to diseased tissue, potentially leading to improved treatments and therapies for lung conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults over 21 years old who have healthy lung function.
Not a fit: Patients with severe lung diseases or conditions that significantly alter lung structure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in the diagnosis and treatment of lung diseases.
How similar studies have performed: Previous research has shown success in creating detailed biological atlases, indicating that this approach has the potential for significant breakthroughs.
Where this research is happening
Rochester, United States
- University of Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Pryhuber, Gloria S — University of Rochester
- Study coordinator: Pryhuber, Gloria S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.