Creating a detailed 3D map of the human brain using advanced imaging techniques
A 3D multimodal micron-scale human brain atlas bridging single cell data, neuropathology and neuroradiology
['FUNDING_OTHER'] · COLD SPRING HARBOR LABORATORY · NIH-10370064
This study is creating a super-detailed 3D map of the human brain to help doctors better understand brain structure and function, which could lead to better ways to diagnose and treat brain conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLD SPRING HARBOR LABORATORY (nih funded) |
| Locations | 1 site (COLD SPRING HARBOR, UNITED STATES) |
| Trial ID | NIH-10370064 on ClinicalTrials.gov |
What this research studies
This research aims to develop a highly detailed, three-dimensional atlas of the human brain that integrates various imaging modalities and histological data. By utilizing advanced techniques such as continuous serial sectioning and diffeomorphic mapping, the project will create a micron-scale reference brain that connects neuroimaging with neuropathological findings. This atlas will serve as a crucial resource for understanding brain structure and function, potentially aiding in the diagnosis and treatment of neurological conditions. Patients may benefit from improved insights into brain disorders through enhanced diagnostic tools and targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing neurological symptoms or conditions.
Not a fit: Patients with acute neurological emergencies or those who do not have access to advanced imaging facilities may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and personalized treatments for neurological conditions.
How similar studies have performed: Previous research has shown success in creating detailed brain atlases for non-human models, suggesting potential for similar advancements in human studies.
Where this research is happening
COLD SPRING HARBOR, UNITED STATES
- COLD SPRING HARBOR LABORATORY — COLD SPRING HARBOR, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MITRA, PARTHA PRATIM — COLD SPRING HARBOR LABORATORY
- Study coordinator: MITRA, PARTHA PRATIM
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.