Creating a comprehensive human genome reference
Maintaining, improving, and providing the human reference
This study is working on creating a new, more complete map of human DNA that includes a wider variety of genetic backgrounds, which will help doctors and researchers better understand how our genes affect health and disease.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10689155 on NIH RePORTER |
What this research studies
This research aims to develop a pan-human genome reference that enhances the existing human genome reference by incorporating a broader representation of genetic diversity. The project will utilize advanced methods to assemble and validate genomic data, ensuring high-quality reference materials are available for researchers and clinicians. By mapping genomic variants, the team will create a resource that allows for better understanding of human genetics and its implications for health and disease. This initiative is designed to be scalable and widely accessible, benefiting a diverse range of stakeholders in the field of genetics.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals undergoing genetic testing or those with genetic disorders seeking more precise diagnoses.
Not a fit: Patients with conditions unrelated to genetic variation or those not requiring genetic analysis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the accuracy of genetic testing and personalized medicine for patients.
How similar studies have performed: Previous research has shown success in enhancing genome references, indicating that this approach has the potential for meaningful advancements.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Wang, Ting — Washington University
- Study coordinator: Wang, Ting
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.