NIH-funded research U01 cooperative agreement

Creating a comprehensive genetic map of Alzheimer's disease using artificial intelligence

Official title: AIM-AI: an Actionable, Integrated and Multiscale genetic map of Alzheimer's disease via deep learning

Funded at University of Texas Hlth Sci Ctr Houston · NIH-10927217 · Data updated 2026-11-12

This study is working on a smart computer program to help understand how genes and brain scans are connected to Alzheimer's disease, with the hope that it will lead to better ways to diagnose and treat the condition for patients like you.

More s Disease research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Sci Ctr Houston
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 15, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$1,291,066
NIH project number5U01AG079847-02
Project IDNIH-10927217 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or those at risk due to genetic factors.

Less likely to help

Patients with other forms of dementia unrelated to Alzheimer's may not receive benefits from this research.

What this research studies

This research aims to develop an advanced AI framework called AIM-AI to analyze genetic, omics, and neuroimaging data related to Alzheimer's disease. By leveraging deep learning techniques, the project seeks to uncover critical genetic factors that contribute to the disease's diagnosis and progression. The interdisciplinary team will focus on making these findings actionable and integrated, allowing for a better understanding of how genetic factors influence Alzheimer's at a cellular level. Patients may benefit from insights that could lead to improved diagnostic tools and targeted therapies.

Why it matters

Potential benefit: If successful, this research could lead to more effective diagnostic tools and personalized treatment options for Alzheimer's disease patients.

How similar studies have gone: Previous research has shown promise in using AI to analyze genetic data for various diseases, indicating potential success for this novel approach in Alzheimer's.

Where this research is happening

  • University of Texas Hlth Sci Ctr Houston
    Houston, United States
    Active

Researchers

  • Principal investigator: Zhao, Zhongming — University of Texas Hlth Sci Ctr Houston
  • Study coordinator: Zhao, Zhongming

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.