Creating a comprehensive brain cell knowledge base for multiple species
An extensible brain knowledge base and toolset spanning modalities for multi-species data-driven cell types
This study is creating a helpful resource that organizes information about different brain cells in humans and other primates, which could lead to better understanding and treatments for brain-related diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Allen Institute NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10875580 on NIH RePORTER |
What this research studies
This research aims to develop a detailed knowledge base that organizes and standardizes information about different types of brain cells across various species, including humans and non-human primates. By creating an interactive resource, the project will facilitate access to a wealth of data on brain cell types, which is essential for advancing our understanding of brain function and disorders. The approach involves building a flexible data model that links cell type information and utilizes advanced techniques like spatial transcriptomics to enhance the accuracy of classifications. Patients may benefit from this research as it could lead to new insights into brain-related diseases and potential treatments.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with neurological disorders or those interested in brain health, particularly those over 21 years old.
Not a fit: Patients with conditions unrelated to brain function or those under 21 years old may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could significantly enhance our understanding of brain cell types and their roles in health and disease, potentially leading to improved treatments for neurological conditions.
How similar studies have performed: Other research initiatives, such as the BRAIN Initiative, have shown success in mapping brain cell types and understanding their functions, indicating that this approach has a solid foundation.
Where this research is happening
Seattle, United States
- Allen Institute — Seattle, United States (Active)
Researchers
- Principal investigator: Mufti, Shoaib — Allen Institute
- Study coordinator: Mufti, Shoaib
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.