Creating a collection of stem cells to study heart diseases
BIOREPOSITORY OF HUMAN INDUCED PLURIPOTENT STEM CELLSFORCARDIOVASCULAR DISEASES (BHIPSC-CVD) - TASK AREA B
This study is creating a special collection of stem cells from blood samples of people with heart conditions, like dilated and hypertrophic cardiomyopathy, to help researchers learn more about these diseases and find better treatments for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11181132 on NIH RePORTER |
What this research studies
This research focuses on developing a biorepository of human induced pluripotent stem cells (iPSCs) specifically for studying cardiovascular diseases. By collecting blood samples from diverse patients, including those with conditions like dilated and hypertrophic cardiomyopathy, researchers can create iPSC lines that mimic the genetic and phenotypic characteristics of these individuals. This approach allows for better understanding of disease mechanisms, drug toxicity screening, and predicting how patients might respond to new treatments. The research aims to enhance the availability of iPSC technology for cardiovascular research and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals with dilated cardiomyopathy, hypertrophic cardiomyopathy, or healthy individuals from diverse racial and ethnic backgrounds.
Not a fit: Patients with cardiovascular diseases not included in the study focus or those who do not belong to the targeted racial and ethnic groups may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for cardiovascular diseases tailored to individual genetic profiles.
How similar studies have performed: Other research has successfully utilized iPSCs for studying various diseases, indicating a promising approach for cardiovascular research.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Wu, Joseph — Stanford University
- Study coordinator: Wu, Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.