Creating a collection of human stem cells to study heart diseases
BIOREPOSITORY OF HUMAN INDUCED PLURIPOTENT STEM CELLSFORCARDIOVASCULAR DISEASES (BHIPSC-CVD)- TASK A. CORE STUDY OPERATIONS
This study is creating a special collection of stem cells from people with heart conditions to help researchers learn more about these diseases and how different treatments might work for patients from all backgrounds.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-11181135 on NIH RePORTER |
What this research studies
This research focuses on developing a biorepository of human induced pluripotent stem cells (iPSCs) specifically for studying cardiovascular diseases. By collecting blood samples from diverse patients, including those with conditions like dilated and hypertrophic cardiomyopathy, researchers can create iPSC lines that mimic the genetic and phenotypic characteristics of these individuals. This allows for better understanding of disease mechanisms, drug toxicity screening, and predicting how patients might respond to new treatments. The project emphasizes inclusivity by recruiting participants from various racial and ethnic backgrounds.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals diagnosed with dilated or hypertrophic cardiomyopathy, as well as healthy volunteers from diverse racial and ethnic backgrounds.
Not a fit: Patients with cardiovascular diseases not represented in the study, or those who do not meet the recruitment criteria, may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and personalized medicine approaches for patients with cardiovascular diseases.
How similar studies have performed: Previous research has successfully utilized iPSCs for studying various diseases, indicating a promising approach for cardiovascular research.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Wu, Joseph — Stanford University
- Study coordinator: Wu, Joseph
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.