Creating a collection of gene mutations in fruit flies to study human biology
A Conditional Loss-of-Function Mutation Collection in Drosophila
This study is creating a new set of gene changes in fruit flies that are similar to human genes, so researchers can better understand how these genes work and how they might relate to human health.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Genetivision Corporation NIH-funded |
| Lab location | 1 site (Stafford, UNITED STATES) |
| Project ID | NIH-10676847 on NIH RePORTER |
What this research studies
This research aims to develop a new collection of 2,800 gene mutations in the fruit fly, Drosophila melanogaster, which are similar to genes found in humans. By using advanced genetic techniques, researchers will be able to turn specific genes on or off in various cell types, allowing for detailed studies of gene function throughout different stages of development. This approach leverages the extensive genetic tools available for fruit flies, which have been instrumental in advancing our understanding of human biology and disease. The findings from this research could provide insights that are directly applicable to human health.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research are individuals with genetic conditions that have parallels in the genes studied in Drosophila.
Not a fit: Patients with conditions unrelated to the genes being studied or those who do not have a genetic basis for their condition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of human genetics and lead to new treatments for genetic diseases.
How similar studies have performed: Previous research using Drosophila as a model organism has successfully contributed to significant advancements in understanding human biology and disease.
Where this research is happening
Stafford, UNITED STATES
- Genetivision Corporation — Stafford, United States (Active)
Researchers
- Principal investigator: Tan, Ying — Genetivision Corporation
- Study coordinator: Tan, Ying
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.