Creating a central hub for pancreas-related knowledge and data
Official title: PanKbase: a community hub for integrated pancreas knowledge
Funded at University of Michigan at Ann Arbor · NIH-11017844 · Data updated 2026-11-12
This study is creating a helpful resource called PanKbase that brings together important information about the pancreas and diabetes, especially focusing on how different types of pancreatic cells work, which could lead to better tests and treatments for people with type 1 diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | February 1, 2024 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $2,000,000 |
| NIH project number | 5U24DK138515-02 |
| Project ID | NIH-11017844 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals affected by type 1 diabetes and those involved in pancreas-related research.
✕Less likely to help
Patients with conditions unrelated to pancreatic function or diabetes may not receive any benefit from this research.
What this research studies
This research aims to develop PanKbase, a comprehensive knowledgebase that integrates diverse datasets related to the pancreas and diabetes, particularly focusing on single cell sequencing and imaging technologies. By connecting fragmented information from various research efforts, the project seeks to enhance our understanding of pancreatic cell types and their roles in diseases like type 1 diabetes. Patients can benefit from improved access to integrated data that may lead to new diagnostic tools and better treatment options. The project will also engage the scientific community to ensure that the knowledge generated is widely disseminated and utilized.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in the understanding and treatment of type 1 diabetes.
How similar studies have gone: Other research initiatives focusing on integrated data approaches in diabetes have shown promise, indicating that this method could be effective.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Parker, Stephen Cj — University of Michigan at Ann Arbor
- Study coordinator: Parker, Stephen Cj
Related research
Other NIH-funded projects on the same topics.
-
Expanding genetic testing for cancer risk in patients and families
This study is working to make it easier for cancer patients in Michigan to get genetic testing for cancer risk by improving how doctors gather family history and assess genetic risks, so that more people can receive the important evaluations they need.
-
HEARTS hypertension and diabetes care in Guatemala
This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.
-
Why the retina can sometimes heal itself and how we might help it heal
This NIH grant explores how inflammation and neural cells interact in the zebrafish retina to understand retinal neuron death and regeneration, with potential implications for human vision.
-
Integrated Heart Health: A HEARTS-based approach to hypertension and diabetes in Guatemala
A study tests a team-based, stepwise care model to improve blood pressure and blood sugar control for people with both hypertension and diabetes in Guatemala.
-
Understanding how work exposures and genes influence ALS risk
A study is building a long-term group of people at higher risk for ALS to see how their jobs, exposures at work, and genes together affect if and when the disease might develop.
-
An integrated mobile health program to reduce SAVA and mental health problems among female sex workers in Kenya
A new mobile health program aims to help female sex workers in Kenya avoid substance abuse, violence, HIV, and depression by delivering group therapy, online resources, and a peer discussion space.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.