NIH-funded research R01 grant

Creating a brain-computer interface to help people with spinal cord injuries control their hand movements

Official title: Development of an EMG-controlled BCI for biomimetic control of hand movement in humans

Funded at Northwestern University at Chicago · NIH-10930831 · Data updated 2026-11-12

This study is working on a new device that helps people with serious spinal cord injuries control their hand movements using signals from their brain, making it easier for them to move their fingers and grip things naturally.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 18, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$614,416
NIH project number5R01NS131953-02
Project IDNIH-10930831 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals with high-level spinal cord injuries who have limited or no hand movement.

Less likely to help

Patients with low-level spinal cord injuries or those without significant motor impairment may not benefit from this research.

What this research studies

This research aims to develop an innovative brain-computer interface (BCI) that allows individuals with high-level spinal cord injuries to control their hand movements more effectively. By utilizing electrical signals from the brain that correspond to muscle activity, the BCI will enable users to not only move their fingers but also control the force of their grip. The approach mimics the natural neuromuscular system, providing a more intuitive way for patients to interact with their environment. Participants will engage in activities that help train the system to interpret their intentions based on brain signals.

Why it matters

Potential benefit: If successful, this research could significantly enhance hand function and independence for individuals with spinal cord injuries.

How similar studies have gone: While there have been advancements in brain-computer interfaces, this specific approach using EMG signals for intuitive control represents a novel and untested method.

Where this research is happening

  • Northwestern University at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Miller, Lee — Northwestern University at Chicago
  • Study coordinator: Miller, Lee

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.