Creating a blood test to monitor transplanted liver cells
Development of a proteomic assay for monitoring transplanted cells and tissues
This study is working on a simple blood test to help people who have received transplanted liver cells by checking if those cells are working well, making it easier for doctors to monitor their health after the procedure.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hepatx Corporation NIH-funded |
| Lab location | 1 site (Palo Alto, United States) |
| Project ID | NIH-11066174 on NIH RePORTER |
What this research studies
This research aims to develop a blood test that can measure the success of transplanted liver cells in patients. By using advanced mass spectrometry techniques, the researchers will identify specific proteins that indicate whether the transplanted cells are functioning properly. This test could provide a non-invasive way to monitor patients who have undergone cell transplantation, particularly for liver diseases. The approach has shown promise in animal studies, and the goal is to translate these findings into human applications.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with liver disease who are considering or have undergone hepatocyte transplantation.
Not a fit: Patients who do not have liver disease or are not candidates for cell transplantation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a reliable method for monitoring the effectiveness of liver cell transplants, improving patient outcomes.
How similar studies have performed: Previous research has successfully developed similar assays in animal models, indicating potential for success in human applications.
Where this research is happening
Palo Alto, United States
- Hepatx Corporation — Palo Alto, United States (Active)
Researchers
- Principal investigator: Schuur, Eric R — Hepatx Corporation
- Study coordinator: Schuur, Eric R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.