Creating a blood test to identify specific brain disorders in dementia patients
Official title: Development of a Blood-based Test for Identifying Synucleinopathy in Patients with Dementia
Funded at Neurodex INC · NIH-10928757 · Data updated 2026-11-12
This study is working on a blood test that can help find brain disorders linked to dementia, so doctors can better choose safe treatments for patients who might be affected by antipsychotic medications.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Neurodex INC NIH-funded |
| Lab location | 1 site (Arlington, United States) |
| Project start | September 23, 2022 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $942,163 |
| NIH project number | 5R44NS130864-03 |
| Project ID | NIH-10928757 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with dementia who may be at risk for synucleinopathies.
✕Less likely to help
Patients with dementia who do not have synucleinopathies or those who are not being considered for antipsychotic treatment may not benefit from this research.
What this research studies
This research focuses on developing a blood-based test that can accurately detect synucleinopathies, which are brain disorders associated with dementia. By using advanced techniques to isolate extracellular vesicles from blood, the researchers aim to identify patients who may be adversely affected by antipsychotic medications. The test is designed to improve the selection of appropriate treatments, thereby enhancing patient safety and care. The study involves both discovery and clinical phases to ensure the test's effectiveness and reliability.
Why it matters
Potential benefit: If successful, this research could lead to a reliable blood test that helps prevent harmful treatments in dementia patients.
How similar studies have gone: Previous research has shown promising results in using similar approaches for detecting synucleinopathies, indicating potential for success in this novel application.
Where this research is happening
-
Neurodex INC
Arlington, United States Active
Researchers
- Principal investigator: Eitan, Erez — Neurodex INC
- Study coordinator: Eitan, Erez
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.