Creating a biorepository for Down syndrome research
The INCLUDE Project Down Syndrome Biorepository (DS-Biorepository)
This study is creating a special collection of biological samples from people with Down syndrome to help researchers learn more about health issues they might face, like Alzheimer's and autism, so we can better understand how Down syndrome affects their lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11001640 on NIH RePORTER |
What this research studies
This research aims to establish a biorepository specifically for individuals with Down syndrome, which will collect and store biological samples to support various studies on co-occurring conditions such as Alzheimer's disease and autism. By analyzing these samples, researchers hope to uncover the underlying mechanisms of how trisomy 21 affects health and development. The project will involve collaboration with multiple research teams and utilize advanced techniques to explore genetic and environmental factors influencing Down syndrome. This biorepository will serve as a vital resource for future investigations into the diverse health challenges faced by individuals with Down syndrome.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals with Down syndrome of all ages, particularly those who may also have co-occurring conditions.
Not a fit: Patients without Down syndrome or those who do not have any associated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals with Down syndrome and their associated health conditions.
How similar studies have performed: Previous research initiatives involving biobanks for genetic and health studies have shown success in uncovering important health insights, indicating a promising potential for this biorepository.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Espinosa, Joaquin M. — University of Colorado Denver
- Study coordinator: Espinosa, Joaquin M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.