Creating a Bioengineered Heart for Transplant
Coordinated Heart Stimulation Testbed: A Platform for Contractile Ventricle Engineering
['FUNDING_R01'] · TEXAS HEART INSTITUTE · NIH-11126622
This project aims to develop a lab-grown heart using human cells to help patients with severe heart failure.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | TEXAS HEART INSTITUTE (nih funded) |
| Locations | 1 site (HOUSTON, UNITED STATES) |
| Trial ID | NIH-11126622 on ClinicalTrials.gov |
What this research studies
Heart failure is a major health problem, and there aren't enough donor hearts for everyone who needs a transplant. This project is working to create a functional, lab-grown heart chamber using human stem cells and 3D printing techniques. Researchers are developing special systems to help these lab-grown heart cells mature properly, so they can eventually form a working heart. The ultimate goal is to engineer a transplantable heart from human cells to address the shortage of donor organs.
Who could benefit from this research
Good fit: Patients with end-stage heart failure who require a heart transplant could potentially benefit from this future technology.
Not a fit: Patients who do not have heart failure or whose condition does not require a heart transplant would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could provide a new source of transplantable hearts, offering hope to patients with end-stage heart failure who currently face long waits for donor organs.
How similar studies have performed: While previous efforts to build functional bioartificial heart chambers have faced challenges, this project proposes a novel integrated platform to overcome these limitations.
Where this research is happening
HOUSTON, UNITED STATES
- TEXAS HEART INSTITUTE — HOUSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HOCHMAN-MENDEZ, CAMILA — TEXAS HEART INSTITUTE
- Study coordinator: HOCHMAN-MENDEZ, CAMILA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.