Creating a 3D printed skin model to study infections
3D Printing of an immunocompetent, epidermal-dermal model
['FUNDING_OTHER'] · DUKE UNIVERSITY · NIH-11093848
This study is creating a special 3D model of skin to help us learn how bacteria can cause infections, especially in kids, so we can find better ways to treat skin problems like impetigo and diabetic foot ulcers.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | DUKE UNIVERSITY (nih funded) |
| Locations | 1 site (DURHAM, UNITED STATES) |
| Trial ID | NIH-11093848 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a 3D bioprinted model of skin to better understand how bacteria in biofilms cause infections, particularly in children. By using this advanced model, researchers aim to replicate the human skin environment more accurately than traditional methods, which often rely on animal models or agar plates. The project will investigate how different bacteria interact with the skin and how they can influence immune responses, potentially leading to better treatments for skin infections like impetigo and diabetic foot ulcers.
Who could benefit from this research
Good fit: Ideal candidates for this research are children under 11 years old who are at risk for skin infections.
Not a fit: Patients with skin infections not caused by biofilm-forming bacteria may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for skin infections, particularly in pediatric patients.
How similar studies have performed: Previous research has shown promise in using bioprinted models for studying infections, indicating a potential for success in this novel approach.
Where this research is happening
DURHAM, UNITED STATES
- DUKE UNIVERSITY — DURHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JONES, AKHENATON-ANDREW DHAFIR — DUKE UNIVERSITY
- Study coordinator: JONES, AKHENATON-ANDREW DHAFIR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.