Creating a 3D model to study kidney development
Nephrogenesis on a chip: an simple modular platform to spatially pattern extracellular matrix, stromal cells, and soluble factors
['FUNDING_R21'] · UNIVERSITY OF DELAWARE · NIH-11039098
This study is creating a special 3D model of a developing kidney to help scientists learn how kidney cells grow and what affects their development, which could lead to better understanding and treatment of kidney diseases.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF DELAWARE (nih funded) |
| Locations | 1 site (Newark, UNITED STATES) |
| Trial ID | NIH-11039098 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a modular 3D model that mimics the environment of the developing kidney, allowing scientists to study how different factors influence kidney cell development. By spatially organizing extracellular matrix components, stromal cells, and soluble factors, the model aims to replicate the conditions necessary for nephron formation. This innovative approach will enable researchers to better understand the mechanisms behind kidney development and disease, providing a valuable tool for future studies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions affecting kidney development or function, as well as those interested in advancements in kidney disease treatment.
Not a fit: Patients with fully developed kidneys and no history of kidney disease may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of kidney diseases by providing insights into nephron development.
How similar studies have performed: Other research has shown success with similar 3D modeling approaches in studying organ development, indicating potential for this method to yield valuable insights.
Where this research is happening
Newark, UNITED STATES
- UNIVERSITY OF DELAWARE — Newark, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GLEGHORN, JASON PAUL — UNIVERSITY OF DELAWARE
- Study coordinator: GLEGHORN, JASON PAUL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.