Creating a 3D model to study brain injuries and their effects
Official title: Lasting Impacts: Dynamic, Fully Natural Bioprinted 3D Human Neurovascular Biomimetic Model to Study Traumatic Brain Injury Pathophysiology
Funded at Lawrence Livermore National Security, LLC · NIH-10928816 · Data updated 2026-11-12
This study is creating a special 3D model of human brain blood vessels to help us learn more about how traumatic brain injuries affect people, with the hope that it will lead to better treatments for those who have experienced such injuries.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lawrence Livermore National Security, LLC NIH-funded |
| Lab location | 1 site (Livermore, United States) |
| Project start | September 15, 2021 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $570,371 |
| NIH project number | 5R33HL159947-04 |
| Project ID | NIH-10928816 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a traumatic brain injury and are facing cognitive or physical challenges as a result.
✕Less likely to help
Patients who have not experienced a traumatic brain injury or those with other unrelated neurological conditions may not benefit from this research.
What this research studies
This research focuses on developing a 3D bioprinted model that mimics human brain blood vessels to better understand the effects of traumatic brain injuries (TBI). By using this advanced model, researchers aim to investigate how TBIs lead to long-term cognitive and physical impairments. The approach combines expertise from multiple institutions to explore the underlying mechanisms of brain injury and its progression. Patients may benefit from insights gained through this research, which could lead to improved treatments and interventions for TBI.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals suffering from the long-term effects of traumatic brain injuries.
How similar studies have gone: Previous research has shown promise in using bioprinted models to study various neurological conditions, indicating that this approach could yield valuable insights.
Where this research is happening
-
Lawrence Livermore National Security, LLC
Livermore, United States Active
Researchers
- Principal investigator: Moya, Monica Lizet — Lawrence Livermore National Security, LLC
- Study coordinator: Moya, Monica Lizet
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.